Gene Expression Profile Reveals Abnormalities of Multiple Signaling Pathways in Mesenchymal Stem Cell Derived from Patients with Systemic Lupus Erythematosus

Figure 7

The correlation of Id-1 mRNA expression with serum TNF-𝛼 levels in SLE patients. (a, b) Id-1 mRNA level was not correlated with antinuclear antibodies (ANA) levels and SLE disease activity index (SLEDAI) score of SLE patients. (c) The serum level of TNF-𝛼 in SLE patients (𝑛=10) were higher than that of normal controls (𝑛=20). **𝑃<0.01 versus normal controls by Student’s t-test. (d) Id-1 mRNA expression was reversely correlated with serum TNF-𝛼 level of SLE patients (𝑃=0.01, 𝑟²=0.55). SLE: systemic lupus erythematosus, Nor: normal controls.

(a)

(b)

(c)

(d)