Research Article
Association of Autoantibodies to BP180 with Disease Activity in Greek Patients with Bullous Pemphigoid
Table 1
Patients’ clinical characteristics at baseline, month 3, and month 6.
| | Clinical characteristics | Statistics | Values () at baseline | Values () at month 3 | Values () at month 6 |
| | | value | | 0.000* | | 0.838 | | | BPDAI (0–360) | Mean SD | 52.5 24.7# | | 1.8 ± 4.5 | | 1.5 ± 4.6 | | | Median (min–max) | 50.0 (2.0–104.0) | | 0.0 (0.0–15.5) | | 0.0 (0.0–17.1) |
| | | value | | 0.000* | | 0.646 | | | ABSIS (0–206) | Mean ± SD | 44.7 ± 21.7# | | 1.7 ± 4.1 | | 1.4 ± 4.3 | | | Median (min–max) | 43.5 (1.5–92.5) | | 0.0 (0.0–14.1) | | 0.0 (0.0–15.7) |
| | | value | | 0.000* | | 0.682 | | | BPDAI pruritus index (0–30) | Mean ± SD | 23.1 ± 7.3 | | 0.5 ± 1.3 | | 0.5 ± 1.7 | | | Median (min–max) | 24.0 (0.0–30.0) | | 0.0 (0.0–5.0) | | 0.0 (0.0–7.0) |
| | | value | | 0.000* | | 0.001* | | | BP180 (U/mL) | Mean ± SD | 87.9 ± 46.6# | | 11.1 ± 12.1 | | 8.7 ± 9.7 | | | Median (min–max) | 88.4 (10.0–190.8) | | 7.2 (2.3–49.1) | | 6.6 (1.9–41.1) |
| | | value | | 0.000* | | 0.115 | | | BP230 (U/mL) | Mean ± SD | 36.5 ± 36.5 | | 18.2 ± 12.9 | | 15.7 ± 13.8 | | | Median (min–max) | 26.4 (1.5–151.2) | | 16.9 (1.4–56.2) | | 9.0 (2.1–59.2) |
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*Wilcoxon’s signed rank test statistically significant; #variable normally distributed.
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