Review Article
Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus: Current Status and Future Direction
Table 1
REVEAL registry demographic and diagnostic comparison.
| | IPAH | CTD | SLE-aPAH | SSc-aPAH |
| Total # of patients | 1251 | 641 | 110 | 399 | Patients newly diagnosed at enrollment (%) | 14 | 15 | 14 | 16 | Age (years) | 50.1 ± 17.5 | 57.1 ± 13.7 | 45.5 ± 11.9 | 61.8 ± 11.1 | Sex, (#) | | | | | Female | 987 | 578 | 104 | 353 | Male | 264 | 63 | 6 | 46 | Race (%) | | | | | White | 74.8 | 71.8 | 37.4 | 83.9 | African-American | 11.7 | 16.5 | 31.8 | 10.9 | Hispanic | 8.3 | 7.5 | 17.8 | 3.6 | Other | 5.2 | 4.2 | 13.1 | 1.6 | Raynaud phenomenon (%) | 1.4 | 26.5 | 13.6 | 32.6 | Renal insufficiency (%) | 3.9 | 6.9 | 4.6 | 8.7 | Time between diagnostic RHC and enrollment (months) | 41.1 ± 44.1 | 27.2 ± 29.9 | 34.4 ± 39.1 | 24.2 ± 24.1 | BNP (pg/mL) | 245.6 ± 427.2 | 432.8 ± 789.1 | 263.8 ± 338.8 | 552.2 ± 977.8 | DLCO (%) | 63.6 ± 22.1 | 44.9 + 18 | 53.3 ± 19.5 | 41.2 ± 16.3 | Immunosuppressive therapy (%) | 1.3 | 11.9 | 22 | 6.8 | Alive at 1 year (%) | 93 | 86 | 94 | 82 |
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