Review Article
Extrahepatic Manifestations and Autoantibodies in Patients with Hepatitis C Virus Infection
Table 2
Comparisons of immunological and histological findings between primary SS and HCV-related SS.
| Variable
| Primary SS | HCV-related SS |
| Autoantibodies
| High frequency of ANA, anti-Ro, and anti-La
| Low frequency of ANA, anti-Ro, and anti-La
| Cryoglobulin | Rare | Common | Hypocomplementemia
| Rare | Common | Lymphocytic capillaritis | Moderate to severe
| Mild to moderate
| Th1/Th2 balance | Th1 predominant | Th2 predominant
| Monoclonal gammopathy
| Low | High | Association of HLA DR-3 | High | Low |
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