Transfer of Maternal Immunity to Newborns of Diabetic Mothers
Table 2
Mean (±SD) immunoglobulin level in colostrum, maternal blood, and cord blood from normoglycemic and hyperglycemic women.
Parameter
Sample
Normoglycemic
Hyperglycemic
Statistical contrast
IgG (mg/dL)
Colostrum
120.8 ± 43.7
82.5 ± 27.7†
Colostrum versus blood ;
Maternal blood
2014.6 ± 261.6*
1649.3 ± 207.8*†
Normo- versus hyperglycemic ;
Cord blood
1940.4 ± 327.4*
2570.9 ± 466.1*#†
IgA (mg/dL)
Colostrum
417.8 ± 51.3
291.5 ± 90.3†
Colostrum versus blood ;
Maternal blood
55.4 ± 7.1*
43.0 ± 5.1*
Normo- versus hyperglycemic ;
Cord blood
24.4 ± 4.7*#
22.5 ± 8.8*#
IgM (mg/dL)
Colostrum
36.2 ± 10.5
36.2 ± 8.5
Colostrum versus blood ;
Maternal blood
52.8 ± 13.8
37.3 ± 6.9†
Normo- versus hyperglycemic ;
Cord blood
13.5 ± 5.3*#
13.0 ± 7.7*#
Within a same group (normo- or hyperglycemic), indicates statistical differences between colostrum and blood and indicates differences between maternal blood and cord blood immunoglobulin levels. Indicates statistical differences in immunoglobulin levels between normo- and hyperglycemic women (in a row).