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Clinical and Developmental Immunology
Volume 2012 (2012), Article ID 962538, 11 pages
http://dx.doi.org/10.1155/2012/962538
Research Article

Vaccination with Enzymatically Cleaved GPI-Anchored Proteins from Schistosoma mansoni Induces Protection against Challenge Infection

1Departamento de Bioquímica, Imunologia do Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil
2Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais (INCT-DT), CNPq MCT, 40110-160 Salvador, BA, Brazil
3Departamento de Biologia Geral do Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil
4Departamento de Patologia Geral do Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil
5Departamento de Ciências Biológicas, Universidade Federal de Ouro Preto, 35400-000 Ouro Preto, MG, Brazil
6Centre for Immunology & Infection, Department of Biology, University of York, Heslington, York YO10 5DD, UK

Received 11 April 2012; Accepted 21 June 2012

Academic Editor: Anderson Sá-Nunes

Copyright © 2012 Vicente P. Martins et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [14 citations]

The following is the list of published articles that have cited the current article.

  • Cristina Toscano Fonseca, Gardênia Braz Figueiredo Carvalho, Clarice Carvalho Alves, and Tatiane Teixeira de Melo, “Schistosoma Tegument Proteins in Vaccine and Diagnosis Development: An Update,” Journal of Parasitology Research, vol. 2012, pp. 1–8, 2012. View at Publisher · View at Google Scholar
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  • Carina S. Pinheiro, Ana Paula Dias Ribeiro, Fernanda C. Cardoso, Vicente P. Martins, Barbara C. P. Figueiredo, Natan R.G. Assis, Suellen B. Morais, Marcelo V. Caliari, Alex Loukas, and Sergio C. Oliveira, “ A multivalent chimeric vaccine composed of Schistosoma mansoni SmTSP-2 and Sm29 was able to induce protection against infection in mice ,” Parasite Immunology, 2014. View at Publisher · View at Google Scholar
  • Soraya Gaze, Patrick Driguez, Mark S. Pearson, Tiago Mendes, Denise L. Doolan, Angela Trieu, Donald P. McManus, Geoffrey N. Gobert, Maria Victoria Periago, Rodrigo Correa Oliveira, Fernanda C. Cardoso, Guilherme Oliveira, Rie Nakajima, Al Jasinskas, Chris Hung, Li Liang, Jozelyn Pablo, Jeffrey M. Bethony, Philip L. Felgner, and Alex Loukas, “An Immunomics Approach to Schistosome Antigen Discovery: Antibody Signatures of Naturally Resistant and Chronically Infected Individuals from Endemic Areas,” Plos Pathogens, vol. 10, no. 3, 2014. View at Publisher · View at Google Scholar
  • James P Hewitson, and Rick M Maizels, “Vaccination against helminth parasite infections,” Expert Review of Vaccines, pp. 1–15, 2014. View at Publisher · View at Google Scholar
  • Vicente P. Martins, Suellen B. Morais, Carina S. Pinheiro, Natan R. G. Assis, Barbara C. P. Figueiredo, Natasha D. Ricci, Juliana Alves-Silva, Marcelo V. Caliari, and Sergio C. Oliveira, “Sm10.3, a Member of the Micro-Exon Gene 4 (MEG-4) Family, Induces Erythrocyte Agglutination In Vitro and Partially Protects Vaccinated Mice against Schistosoma mansoni Infection,” Plos Neglected Tropical Diseases, vol. 8, no. 3, 2014. View at Publisher · View at Google Scholar
  • Gardênia Braz Figueiredo de Carvalho, Lucila Gonçalves Grossi Pacífico, Deborah Laranjeira Ferreira Pimenta, Liliane Maria Vidal Siqueira, Andréa Teixeira-Carvalho, Paulo Marcos Zech Coelho, Carina da Silva Pinheiro, Ricardo Toshio Fujiwara, Sergio Costa Oliveira, and Cristina Toscano Fonseca, “Evaluation of the use of C-terminal part of the Schistosoma mansoni 200kDa tegumental protein in schistosomiasis diagnosis and vaccine formulation,” Experimental Parasitology, 2014. View at Publisher · View at Google Scholar
  • Megan L. Mickum, Nina S. Prasanphanich, Jamie Heimburg-Molinaro, Kristoffer E. Leon, and Richard D. Cummings, “Deciphering the glycogenome of schistosomes,” Frontiers in Genetics, vol. 5, 2014. View at Publisher · View at Google Scholar
  • G. Abdel-Monaem, A. Farid, I. Rabia, and A. El-Amir, “Evaluation of Echinostoma liei worm, metacercaria and redia antigens for schistosomiasis control,” Experimental Parasitology, 2015. View at Publisher · View at Google Scholar
  • Shereen F. Mossallam, Eglal I. Amer, Radwa E. Ewaisha, Amal M. Khalil, Hamida M. Aboushleib, and Mohammed Bahey-El-Din, “Fusion protein comprised of the two schistosomal antigens, Sm14 and Sm29, provides significant protection against Schistosoma mansoni in murine infection model,” BMC Infectious Diseases, vol. 15, no. 1, 2015. View at Publisher · View at Google Scholar
  • Tianfang Wang, Min Zhao, Bronwyn A. Rotgans, April Strong, Di Liang, Guoying Ni, Yanin Limpanont, Pongrama Ramasoota, Donald P. McManus, and Scott F. Cummins, “Proteomic Analysis of the Schistosoma mansoni Miracidium,” Plos One, vol. 11, no. 1, 2016. View at Publisher · View at Google Scholar