Comparison of Characteristics of Connective Tissue Disease-Associated Interstitial Lung Diseases, Undifferentiated Connective Tissue Disease-Associated Interstitial Lung Diseases, and Idiopathic Pulmonary Fibrosis in Chinese Han Population: A Retrospective Study
Table 2
Comparison of clinical characteristics among CTD-ILD, UCTD-ILD, and IPF patients.
CTD-ILD
UCTD-ILD
IPF
P1
P2
P3
Subject (n)
63
65
75
Age (years)
0.05
0.05
0.614
Sex (M/F)
20/43
41/24
52/23
0.000
0.000
0.434
Ever smoker n (%)
15 (24)
35 (54)
35 (47)
0.000
0.005
0.397
Symptoms n (%)
Cough
45 (71)
65 (100)
67 (89)
0.000
0.007
0.007
Sputum
33 (52)
51 (78)
48 (64)
0.002
0.167
0.061
Dyspnea
35 (56)
49 (75)
57 (76)
0.018
0.011
0.933
Fatigue
21 (33)
27 (42)
27 (36)
0.338
0.743
0.502
Hemoptysis
0 (0)
5 (8)
4 (5)
0.074
0.177
0.824
Chest discomfort
0 (0)
8 (12)
16 (21)
0.004
0.000
0.158
Chest pain
0 (0)
11 (17)
13 (17)
0.001
0.001
0.949
Skin rash
14 (22)
16 (25)
0 (0)
0.749
0.000
0.000
Arthralgia
19 (30)
14 (19)
1 (1)
0.265
0.000
0.000
Dry eyes/dry mouth
5 (8)
7 (11)
0 (0)
0.583
0.043
0.012
Raynaud’s phenomenon
9 (14)
10 (15)
0 (0)
0.861
0.002
0.001
Proximal muscle weakness
8 (13)
0 (0)
0 (0)
0.008
0.004
—
Muscle pain
13 (21)
0 (0)
0 (0)
0.000
0.000
—
Recurrent unexplained fever
4 (6)
9 (14)
7 (9)
0.160
0.519
0.403
Leg/foot swelling
4 (6)
6 (9)
10 (13)
0.781
0.176
0.447
Face swelling
2 (3)
0 (0)
0 (0)
0.462
0.401
—
Oral ulceration
2 (3)
0 (0)
0 (0)
0.462
0.401
—
P1: Possibility when comparing CTD-ILD group and UCTD-ILD group. P2: Possibility when comparing CTD-ILD group and IPF group. P3: Possibility when comparing UCTD-ILD group and IPF group.
