Prediction of IL4 Inducing Peptides

Table 2

Frequency of best motifs discovered using MERCI software in IL4 inducers and IL4 noninducers.

Class of motifs	Found in IL4 inducers	Frequency	Found in IL4 noninducers	Frequency
None	I-N-KI	28	P-D-D-P	22
Koolman-Rohm	[acidic][aliphatic]-K-[aromatic] [neutral]-K	31	L[aliphatic][aliphatic]-L [aliphatic]-L[aliphatic]	29
Betts-Russell	[hydrophobic]K[hydrophobic] [small][polar]-P[charged]	51	[aliphatic][hydrophobic][aliphatic] [hydrophobic]; [aliphatic]-L-[aliphatic]	41

Negative sign (−) represents the gaps with the length of 1–5 residues at that position.