Review Article

Mesenchymal Stem Cells in Immune-Mediated Bone Marrow Failure Syndromes

Table 2

Immunosuppressive functions of BM MSCs on various immune cell types.

Cell typesMSC function

T cellsInhibition of T lymphocyte proliferation/activation
B cellsInhibition of B cell proliferation/maturation/antibody secretion
NK cellsInhibition of NK proliferation/function
DCsInhibition of DC maturation/function
TregsPromotion of Treg maturation and cell function