The Correlations of Disease Activity, Socioeconomic Status, Quality of Life, and Depression/Anxiety in Chinese Patients with Systemic Lupus Erythematosus

Table 3

Disease status and quality of life in the anxious and depressed subgroups.

Variables	SAS			SDS
	<50	≥50	𝑃	<53	≥53	𝑃
Age^a	32.3 ± 10.3	35.2 ± 9.6	0.32	32.4 ± 10.6	34.0 ± 9.4	0.51
Sex^b
Male	6 (9.5)	1 (6.3)	0.68	7 (13.2)	0 (0.0)	0.05
Female	57 (90.5)	15 (92.7)		46 (86.8)	26 (100.0)
BMI	21.2 ± 2.7	21.1 ± 2.9	0.93	21.1 ± 2.8	21.4 ± 2.6	0.61
Marital status^b
Single	15 (23.8)	1 (6.3)	0.25	14 (26.4)	2 (7.7)	0.11
Married	48 (76.2)	15 (93.7)		38 (73.6)	24 (92.3)
Education^b
<9 years	29 (46.0)	14 (87.5)	0.003	23 (43.4)	20 (76.9)	0.005
≥9 years	34 (54.0)	2 (12.5)		30 (56.6)	6 (23.1)
Work status^b
Working	15 (23.8)	0 (0)	0.03	13 (24.5)	2 (7.7)	0.07
Unemployed	48 (76.2)	16 (100.0)		40 (75.5)	24 (92.3)
Income/person^b
≤2000 yuan	36 (57.1)	14 (87.5)	0.02	28 (52.8)	22 (84.6)	0.006
>2000 yuan	27 (42.9)	2 (12.5)		25 (47.2)	4 (15.4)
Menstrual history^b
Normal	39 (68.4)	9 (60.0)	0.54	36 (79.2)	12 (46.2)	0.006
Abnormal	18 (31.6)	6 (40.0)		10 (20.8)	14 (53.8)
Years since diagnosis of SLE^b
<1	11 (17.5)	2 (12.5)	0.85	10 (18.9)	3 (11.5)	0.63
1–5	31 (49.2)	9 (56.3)		27 (50.9)	13 (50.0)
>5	21 (33.3)	5 (31.2)		16 (30.2)	10 (38.5)
SLEDAI^a	10.4 ± 7.3	17.1 ± 14.7	0.01	10.3 ± 7.7	14.8 ± 12.1	0.046
Domains of SF-36
PCS^a	256.7 ± 60.7	158.1 ± 51.7	<0.0001	264.0 ± 58.6	181.1 ± 61.5	<0.0001
MCS^a	282.8 ± 67.0	161.7 ± 60.1	<0.0001	295.1 ± 56.9	183.3 ± 72.9	<0.0001
PF^a	86.8 ± 14.1	61.3 ± 28.8	<0.0001	88.9 ± 12.2	66.9 ± 26.1	<0.0001
RP^a	52.4 ± 42.5	4.7 ± 13.6	0.0001	57.1 ± 43.1	13.5 ± 23.7	<0.0001
BP^a	63.8 ± 26.8	54.0 ± 20.0	0.18	63.6 ± 26.6	58.2 ± 24.4	0.38
GH^a	53.6 ± 14.0	38.1 ± 13.3	0.0001	54.4 ± 12.6	42.5 ± 16.8	0.0007
VT^a	66.6 ± 16.1	48.1 ± 19.5	0.0002	68.8 ± 15.0	50.8 ± 18.7	<0.0001
SF^a	86.7 ± 29.3	64.1 ± 34.4	0.01	91.7 ± 26.8	62.5 ± 31.6	0.0001
RE^a	67.2 ± 38.1	0 ± 0	<0.0001	71.7 ± 36.0	16.7 ± 33.0	<0.0001
MH^a	62.3 ± 15.1	49.5 ± 19.4	0.006	62.9 ± 13.9	53.4 ± 20.3	0.017

aMean ± SD. ^bNumber (percentage).
SAS: revised Self-Rating Anxiety Scale; SDS: revised Self-Rating Depression Scale; PCS: physical components summary; MCS: mental components summary; PF: physical functioning; RP: role limitations due to physical problems; RE: role limitations due to emotional problems; SF: social functioning; MH: mental health; VT: energy/vitality; BP: body pain; GH: general health perception.