Indoleamine 2,3-Dioxygenase: Expressing Cells in Inflammatory Bowel Disease—A Cross-Sectional Study
Figure 7
CD123+/IDO+ cells in colonic mucosa from IBD (UC and CD) patients. (a) Representative immunoperoxidase of CD123/IDO expression in non-inflamed colonic tissue (upper panel), in tissue from an active CD patient (middle panel), and in colonic mucosa from an active UC patient (lower panel). From the left to the right photomicrographs represent mucosa, submucosa, muscular, and adventitia. Arrows depict CD123 (in brown)/IDO (in pink) immunoreactive positive cells (X320). (b) Bars indicate immunohistochemistry analysis of IDO-producing cells in non-inflamed colonic tissues, in tissues from active CD patients, and in colonic mucosa from active UC patients. Results are expressed as median (black line), 10th, 25th, 75th, and 90th percentiles. Yellow line represents the mean.
