Indoleamine 2,3-Dioxygenase: Expressing Cells in Inflammatory Bowel Disease—A Cross-Sectional Study

Table 2

Laboratory variables of Crohn’s disease and ulcerative colitis patients.

Variable	Healthy donors; (𝑛=10)	Active CD patients; (𝑛=6)	Inactive CD patients; (𝑛=8)	Active UC patients; (𝑛=10)	Inactive UC patients; (𝑛=10)
ESR, mm Hg
Mean ± SD		19.6 ± 10.9	5.9 ± 2.8^a	28.4 ± 14.4	6.5 ± 4.3^b
Median		18.0	6.0	27.0	6.0
Range		7–36	2–11	15–57	1–71
CRP, mg/dL
Mean ± SD		2.8 ± 3.2	0.34 ± 0.22^c	0.82 ± 0.71	0.30 ± 0.16
Median		0.97	0.28	0.71	0.30
Range		0.1–6.5	0.06–0.80	0.1–1.9	0.02–2.98
Haemoglobin, g/dL
Mean ± SD		13.2 ± 1.4	15.7 ± 1.6^d	12.9 ± 3.1	14.3 ± 2.6
Median		12.7	15.9	12.2	15.1
Range		11.5–15.1	13.1–18.1	9.8–18.2	8.9–17.0
Platelets, cells/L
Mean ± SD		255.2 ± 72.9	216.7 ± 33.5	318.7 ± 128.9	286.8 ± 113.3
Median		288.0	214	292.0	227.0
Range		161–322	161–258	146–570	116–518
Leucocytes, ×10^9 cells/L
Mean ± SD		5.9 ± 1.6	5.7 ± 1.1	7.1 ± 3.0	6.2 ± 2.1
Median		6.0	5.6	6.5	5.7
Range		4.4–8.4	4.2–8.2	2.4–12.6	3.5–10.3
Lymphocytes, %
Mean ± SD		19.2 ± 11.3	26.9 ± 9.3	29.0 ± 8.9	28.0 ± 8.0
Median		18.0	27.7	29.0	28.3
Range		8.3–37.8	14.2–41.0	15.0–41.5	18.0–45.2
Monocytes, %
Mean ± SD		7.7 ± 4.2	7.7 ± 2.3	7.7 ± 3.2	6.7 ± 2.1
Median		6.4	7.0	8.1	6.4
Range		4.3–15.0	4.5–11.3	2.0–14.6	4.0–11.2
Polymorphonuclear cells, %
Mean ± SD		68.3 ± 8.6	64.1 ± 10.5	58.6 ± 13.7	60.5 ± 13.9
Median		70.5	63.7	61.4	62.0
Range		53.7–75.6	50.0–77.5	34.0–75.0	23.0–77.0

CD: Crohn’s disease patient group; UC: ulcerative colitis patient group.
^aActive CD versus inactive CD; 𝑃=0.003.
^bActive UC versus inactive UC; 𝑃<0.001.
^cActive CD versus inactive CD; 𝑃=0.035.
^dActive CD versus inactive CD; 𝑃=0.010.