Immunomodulatory Effect of Bisphosphonate Risedronate Sodium on CD163⁺ Arginase 1⁺ M2 Macrophages: The Development of a Possible Supportive Therapy for Angiosarcoma

Figure 4

Schematic representation of immunomodulatory effect of DTX and RS together with DTX. RS modulates the chemokines and cytokines from M2 macrophages, and induces an antitumor immune response in the tumor microenvironment.