Correlation of Increased Blood Levels of GITR and GITRL with Disease Severity in Patients with Primary Sjögren’s Syndrome

Table 1

Characteristics of pSS patients and the control subjects.

	pSS; (𝑛=41)	Control; (𝑛=29)
Age (years)	36.42±18.71	34.53±21.47
Sex (female/male)	39/2	28/1
Disease duration (months)	36.33±42.25	—
Arthritis (%)	6 (14.63)	—
Fever (%)	8 (19.51)	—
Anemia (%)	12 (29.27)	—
Leukopenia (%)	20 (48.78)	—
Thrombocytopenia (%)	4 (9.76)	—
Renal disease (%)	7 (17.07)	—
Pulmonary interstitial changes (%)	5 (12.20)	—
Autoimmune liver disfunction (%)	4 (9.76)	—
ANA positive (%)	36 (87.80)	—
A—SSA positive (%)	34 (82.93)	—
A—SSB positive (%)	19 (46.34)	—
ESR (mm/H)	56.75±39.38	—
CRP (mg/L)	4.86±3.21	—
IgG (g/L)	24.76±8.12	—
IgM (g/L)	1.97±1.87	—
IgA (g/L)	3.76±1.51	—
RF (IU/L)	67.79±32.47	—
Focus index (1–3)	1.56±0.77	—

pSS: primary Sjögren’s syndrome; ANA: antinuclear antibody; A-SSA: anti-Ro/SSA antibody; A-SSB: anti-La/SSB antibody; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; IgG: immunoglobulin G; IgM: immunoglobulin M; IgA: immunoglobulin A; RF: rheumatoid factor; Focus index: the number of foci per 4 mm² of tissue.
Values are expressed as mean ± standard deviation.