Research Article
Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1
Table 1
Reduced stem and progenitor cell content in ALL bone marrow.
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Limiting dilution assays were conducted to determine the number of long term culture initiating cells (LTC-IC) and colony-forming cells (CFC) within mononuclear and CD34+ cell fractions from bone marrow (BM) acute lymphoblastic leukemia (ALL). The results represent median (range) values and correspond to the percentage of LTC-IC and CFC within mononuclear or CD34+ cell fractions. **Significantly lower () than in control BM. |