Research Article

Allergenic Characterization of New Mutant Forms of Pru p 3 as New Immunotherapy Vaccines

Figure 5

(a) The ratio between IFNγ and IL4 for T cell line supernatants stimulated with Pru p 3 and its mutant forms is represented ( ). Statistical analysis was performed by a paired-samples Wilcoxon test ( ). Medians (—) and ranges (bars) are shown. (b) GATA-3, Fox p 3, T-bet, and RORγ τ relative gene expression levels for T cell lines from peach-allergic patients ( ). The results are expressed in fold change comparing nonstimulated with stimulated conditions, and statistical significance is indicated ( ) after performing a Wilcoxon test for paired samples. Medians (—) and ranges (bars) are represented.
385615.fig.005a
(a)
385615.fig.005b
(b)