Clinical Study
Immunophenotyping in BK Virus Allograft Nephropathy Distinct from Acute Rejection
Table 1
Clinical characteristics of patients that participated in this study.
| | Characteristics | BKVN () | AR () | SF () | value |
| | Gender, male (%) | 16 (72.73) | 19 (61.29) | 8 (66.67) | 0.686 | | Age (years) | | | | 0.527 | | Donor age (years) | | | | 0.349 | | Banff 97 (IA : IB : IIA : IIB) | — | 4 : 6 : 11 : 10 | — | — | | Positive pretransplant PRA () | 0 | 0 | 0 | — | | Previous transplant | 0 | 0 | 0 | — | | Cold ischemic time (h) | | | | 0.473 | | Warm ischemic time (min) | | | | 0.724 | | Induction with IL-2R antibody, (%) | 22 (100) | 31 (100) | 12 (100) | — | | Baseline immunosuppressants | | | | 0.118 | | MMF + Tac + Pred | 21 | 23 | 9 | | | MMF + CsA + Pred | 1 | 8 | 3 | | | MPA (mg·h/L) | | | | <0.001 | | Tac level (ng/mL) | | | | 0.410 | | Time of biopsy after Tx (month) | 14 (10–21) | 15 (2–25) | 6 (2–16) | 0.10 |
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BKVN: BK virus nephropathy; AR: acute rejection; SF: stable allograft function; PRA: panel-reactive antibody; IL: interleukin; MMF: mycophenolate mofetil; Pred: prednisolone; Tac: Tacrolimus; CsA: cyclosporine A; MPA: mycophenolic acid; : area under the concentration curve from 0 to 12 hours; Tx: transplantation.
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