Induction of Antinuclear Antibodies by De Novo Autoimmune Hepatitis Regulates Alloimmune Responses in Rat Liver Transplantation
Figure 4
Donor specific alloantibody (DSA) response during the rejection phase after OLT. The DSA response against donor DA splenocytes was measured by flow cytometry as described in the Materials and Methods section. Histograms (representative of four individuals) show the percentage of DA splenic cells recognized by DSA (IgG and IgM) in the sera of OLT (IgG: ×16 dilution, IgM: ×256 dilution) at day 7 after OLT. *, **Significantly different compared with the control PBS group () ( and 0.01, resp., Student’s t-test).
