Journal of Immunology Research / 2013 / Article / Tab 3

Research Article

The Diagnostic Value of Transcription Factors T-bet/GATA3 Ratio in Predicting Antibody-Mediated Rejection

Table 3

Histologic lesion of renal allograft.

C4d(+) ABMR
( )
C4d(−) ABMR
( )
TCMR
( )
12 13 23

PTC inflammation, (%)11 (100%)5 (100%)4 (40%)0.0030.031
PTC score 0.7040.0070.021
Glomerulitis, (%)11 (100%)5 (100%)6 (60%)0.0230.111
Glomerulitis score 0.7380.0010.010
Tubulitis, (%)8 (72.7%)4 (80%)10 (100%)0.7630.0820.157
Tubulitis score 0.7560.0040.010
Intimal arteritis, (%)7 (63.6%)3 (60%)3 (30%)0.8930.1330.280
Interstitial inflammation score 0.0640.9260.067
Intraglomerular immunohistological analysis
 T-bet (cells/glomeruli) 0.8080.0390.020
 GATA3 (cells/glomeruli) 0.1560.0420.401
 T-bet/GATA3>19 (81.8%)4 (80%)1 (10%)0.9330.0010.009
Interstitial immunohistological analysis
 T-bet (cells/mm2) 0.6790.1580.280
 GATA3 (cells/mm2) 0.6360.6800.434
 T-bet/GATA3>19 (81.8%)5 (100%)9 (90%)0.3240.6020.480

ABMR: antibody-mediated rejection; TCMR, T-cell-mediated rejection.
12 means value for C4d(+) ABMR group and C4d(−) ABMR group, 13 means value for C4d(+) ABMR group and TCMR group, 23 means value for C4d(−) ABMR group and TCMR group.

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