Journal of Immunology Research / 2013 / Article / Fig 2

Review Article

Evaluating the Immunogenicity of Protein Drugs by Applying In Vitro MHC Binding Data and the Immune Epitope Database and Analysis Resource

Figure 2

An example of matrices used to generate class II HLA prediction methods. Common prediction methods rely on the derivation of specific matrices that quantify the positive or negative contribution of the 20 different amino acid types to the overall binding affinity for each position.

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