Journal of Immunology Research / 2013 / Article / Tab 2

Clinical Study

Clinical Differences between Men and Women with Psoriatic Arthritis: Relevance of the Analysis of Genes and Polymorphisms in the Major Histocompatibility Complex Region and of the Age at Onset of Psoriasis

Table 2

Differences between men and women according to age at psoriasis onset (cutoff: 40 years).
(a) Age at psoriasis onset <40

Variable MenWomen values
n: 45n: 40

Age (yr) NS
Arthritis onset age (yr) NS
Psoriasis onset age (yr) NS
Psoriasis duration (yr) 0.07
Arthritis duration (yr) NS
Psoriasis-arthritis latency (yr) <0.01
Family history44.4%50%NS
Oligoarthritis46.7%40%NS
Polyarthritis17.7%37.5%<0.05
Axial disease33.3%22.5%NS
DIP disease26.7%40%NS
Nail disease37.8%52.5%NS
Enthesitis35.6%27.5%NS
Dactylitis25.5%35%NS
Erosive disease33.3%40%NS
HAQ NS
SJC NS
TJC NS
PASI NS

(b) Age at psoriasis onset >40

Variable Men Women values
n: 10n: 15

Age (yr) 0.03
Arthritis onset age (yr) NS
Psoriasis onset age (yr) <0.05
Psoriasis duration (yr) NS
Arthritis duration (yr) NS
Psoriasis-arthritis latency (yr) NS
Family history10%13.3%NS
Oligoarthritis0%20%NS
Polyarthritis30%53.3%NS
Axial disease70%33.3%NS
DIP disease30%13.3%NS
Nail disease30%20%NS
Enthesitis30%20%NS
Dactylitis 30%20%NS
Erosive disease40%46.7%NS
HAQ NS
SJC NS
TJC NS
PASI NS

DIP: distal interphalangeal joint. HAQ: Health Assessment Questionnaire. SJC: swelling joint count. TJC: tender joint count. PASI: Psoriasis Area and Severity Index.

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