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Journal of Immunology Research
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Journal of Immunology Research
/
2013
/
Article
/
Tab 1
/
Research Article
Persistent Suppression of Type 1 Diabetes by a Multicomponent Vaccine Containing a Cholera Toxin B Subunit-Autoantigen Fusion Protein and Complete Freund’s Adjuvant
Table 1
NOD mouse treatment groups for rVV-mediated suppression of hyperglycemia.
Groups
Treatment (i.p. and s.c. inoculation)
PFU (rVV)
Age at injection
1 (
)
PBS (naive)
0
5 and 7 wks
2 (
)
CFA (1 : 0)
0
5 and 7 wks
3 (
)
CFA (1 : 10)
0
5 and 7 wks
4 (
)
CFA (1 : 100)
0
5 and 7 wks
5 (
)
rVV-CTB::GAD + CFA (1 : 0)
2 × (5 × 10
7
)
5 and 7 wks
6 (
)
rVV-CTB::GAD + CFA (1 : 10)
2 × (5 × 10
7
)
5 and 7 wks
7 (
)
rVV-CTB::GAD + CFA (1 : 100)
2 × (5 × 10
7
)
5 and 7 wks
8 (
)
rVV-CTB::GAD
2 × (5 × 10
7
)
5 and 7 wks