Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma
Association of concomitant HIF-2α, TWIST, and CXCR4 high expression with LNM in PTCs. Columns correspond to immunostaining for HIF-2α, TWIST, and CXCR4, respectively. The first row is the immunostaining of a representative of PTC without LNM showing only HIF-2α high expression (a), low expression of TWIST (b), and CXCR4 (c); the second row is the immunostaining of a representative of PTC with LNM showing high expression of HIF-2α (d), TWIST (e), and CXCR4 (f). All the pictures are in high-power fields (×400).
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