Selection of Conserved Epitopes from Hepatitis C Virus for Pan-Populational Stimulation of T-Cell Responses
Figure 5
Analysis of HCV-specific CTL epitope set selection. (a) The figure depicts the largest PCC that was reached by HCV-specific CTL epitope combinations containing 3, 4, 5, and 6 epitopes (optimal combinations). As shown, with just 3 epitopes it is possible to reach a and 6 epitopes were required to reach a %. (b) We found 15 distinct combinations of 6 epitopes each reaching a % within the 17 invariant HCV-specific CTL epitopes. In the figure, we depicted the sequence of peptides (-axis) that were included in the mentioned epitope combinations and the times that were included (-axis).
