Journal of Immunology Research / 2013 / Article / Fig 1

Review Article

Understanding Dendritic Cells and Their Role in Cutaneous Carcinoma and Cancer Immunotherapy

Figure 1

The distribution of cutaneous dendritic cell subsets in normal skin versus human squamous cell carcinoma (SCC). The human skin contains four main subsets of DCs which can be distinguished based on the differential expression of surface molecules in the steady state (left). Representative immunohistochemistry (right) demonstrating the relative distribution of DC subset markers: (a) CD207/Langerin, (b) CD11c, (c) CD1c/BDCA-1, and (d) CD303/BDCA-2.