Cell-Mediated Immune Responses in Paraneoplastic Neurological Syndromes

Figure 2

The same Hu antigen is present in both nervous tissue and tumor tissue. Cytotoxic T lymphocytes (CTLs) recognizing it are found in tumors and in the peripheral blood and nervous system. The clones of the TCR receptor appear to be similar in all three locations (based on the findings reported in [35, 63]).