Enteropathic Spondyloarthritis: From Diagnosis to Treatment

Table 1

Classification and features of articular involvement subsets in inflammatory bowel disease (IBD).

Peripheral			Axial
Type 1	Type 2	Type 3	Isolated sacroiliitis	Spondylitis
(i) Pauciarticular (less than 5 joints); (ii) Asymmetric involvement; (iii) Acute, self-limiting attack (<10 weeks); (iv) Usually coincides with relapse of IBD; (v) Strongly associated with other extra-intestinal manifestations; (vi) Lower limbs more affected; (vii) Associated with HLA DRB1, B35, B27	(i) Polyarticular (5 or more joints); (ii) Symptoms persist for months or even years; (iii) May be erosive; (iv) Runs a course independent of IBD; (v) Affects both large and small joints; (vi) Strongly associated with uveitis; (vii) Associated with HLA B44	(i) Both axial and peripheral involvement	(i) Asymptomatic; (ii) Usually non progressive disease	(i) Usually precede the onset of IBD; (ii) Runs a course independent of IBD; (iii) Clinical course is similar to idiopathic ankylosing spondylitis; (iv) Disease progression leads to increasing immobility and ankylosing; (v) Associated with uveitis; (vi) Strongly associated with HLA B27