Review Article
Autoimmune Cytopenias in Chronic Lymphocytic Leukemia
Table 4
Reported incidence of AIHA in fludarabine containing regimen treated patients with CLL.
| Reference | No. of AIHA cases/no. of patients evaluated | Relative number of AIHA (%) | Type of therapy given |
| Di Raimondo et al. [49] | 13/112 | 11 | FAMP alone | Myint et al. [50] | 12/59 | 21 | FAMP alone | Mauro et al. [19] | 3/121 10/559 | 2.5 1.8 | FAMP + prednisone Chlorambucil + prednisone |
Catovsky and Richards [51] | 47/387 21/194 9/198 | 12 11 5 | Chlorambucil FAMP FC | Borthakur et al. [52]* | All cases 17/300 DAT-positive 3/300 | All cases 5.8 DAT-positive 1.4 | FCR | Hallek et al. [53] | 4/249 3/404 | 1% <1% | FC FCR |
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ā*Three out 17 patients with AIHA had a positive-DAT, while the remaining 14 patients had a negative-test.
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