Protective Effects of HBSP on Ischemia Reperfusion and Cyclosporine A Induced Renal Injury

Figure 5

Myeloperoxidase (MPO)+ cells (dark red color), detected by Immunostaining, were mainly located in tubular lumens (e, f) and interstitial areas (b–e); and a few were also seen in tubular areas (a, c) and glomerular areas. MPO+ cells were significantly increased by IR and CsA but decreased by HBSP (g). The yellow arrow indicated a MPO+ cell with apoptotic feature (f). Data are expressed as mean number in the high power field of each group (mean ± SEM; 𝑛=6). ^∗𝑃<0.05; ^∗∗𝑃<0.01.

(a) Normal

(b) I only

(c) IR

(d) IR + CsA

(e) IR + CsA + HBSP

(f) IR + HBSP

(g)