Sleep Loss as a Factor to Induce Cellular and Molecular Inflammatory Variations

Table 1

Differential effect of sleep loss time upon glucocorticoid levels.

Human	Cortisol	Reference
TSD 1 night	↑	[34]
TSD 40 hours	= or ↓	[40]
TSD 40 hours	=	[39]
SR 2 hours TIB/1 night	=	[36]
SR 3 hours TIB/4 days	↓	[37]
SR 6 hours TIB/6 days	=	[41]
Rodents	Costicosterone	Reference
RSD 72 hours	↑	[32]
RSD 96 hours	↑	[33]
RSR with 6 hours of SO/21 days	=	[33]

The table illustrates the differential effect of acute sleep deprivation and sleep restriction upon glucocorticoid levels. Representative samples present in this table were measured within the first four hours after wakefulness in humans or at the beginning of the light phase in rodents.
Abbreviations: TSD: total sleep deprivation; SR: sleep restriction; TIB: time in bed; RSD: REM sleep deprivation; SO: sleep opportunity; ↑: increase; =: not change; ↓: decrease.