Research Article

Potential Immune Modularly Role of Glycine in Oral Gingival Inflammation

Figure 3

Effect of IL-1β and glycine treatment on the mRNA expression of the proinflammatory cytokines IL6 (a) and IL8 (b). Confluent cultures of gingival keratinocytes were treated with IL-1β either alone or in combination with glycine to induce inflammatory conditions in vitro. Glycine administration to inflammatory challenged gingival keratinocytes resulted in a decreased proinflammatory cytokine mRNA expression of both IL6 (a) and IL8 (b). Results are presented as means ± SD ( ); difference between groups following ANOVA analysis.