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Clinical and Developmental Immunology
Volume 2013, Article ID 869521, 7 pages
http://dx.doi.org/10.1155/2013/869521
Clinical Study

Viral Aetiology in Adults with Acute Upper Respiratory Tract Infection in Jinan, Northern China

1Shandong Medicinal Biotechnology Centre, Key Laboratory for Modern Medicine and Technology of Shandong Province, Key Laboratory for Virology of Shandong Province, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, Jinan 250062, China
2Central Laboratory, Affiliated Jinan Central Hospital of Shandong University, Jinan 250013, China
3Department of Respiratory, Affiliated Jinan Central Hospital of Shandong University, Jinan 250013, China

Received 15 January 2013; Revised 25 March 2013; Accepted 25 March 2013

Academic Editor: Mario Clerici

Copyright © 2013 Yanqin Lu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Our study investigated the epidemiology of respiratory viruses in adult patients with upper respiratory tract infection (URTI) between August 2009 and September 2010 in Jinan, northern China. Nasal and throat swabs ( ) were collected from adult patients with URTIs. Nine respiratory-related viruses, including IFV, PIV, HRV, HMPV, HBoV, HCoV, ADV, RSV, and EV, were detected in all samples by conventional and reverse transcription polymerase chain reactions. Positive detection rate for respiratory virus was 38.76% and codetection rate was 4.70% in adults with acute respiratory tract infections. IFV (20.81%) was the dominant agent detected and IFVB had a higher incidence (12.58%) than IFVA (7.72%). Detection rates of 8.22%, 5.03%, 3.69%, and 2.52% were observed for HBoV, HRV, EV, and RSV, respectively. HCoV had the lowest detection rate of 0.50%. HBoV, HRV, EV, and ADV infection rates were higher in the 14–25-year-old group than in the 26–65-year-old group. Codetection rates were higher (7.52%) in the 14–25-year-old group than in the older age group (2.64%). The spectrum of respiratory virus infection in adult patients with URTIs was different in Jinan compared with other cities in China.