Clinical Study

Immune Response following Liver Transplantation Compared to Kidney Transplantation: Usefulness of Monitoring Peripheral Blood CD4+ Adenosine Triphosphate Activity and Cytochrome P450 3A5 Genotype Assay

Table 3

Occurrence of infection in LT and KT patients according to IMK ATP levels.

InfectionGroup LT-L ( )Group LT-H ( ) value
IMK < 225IMK > 225

Bacterial infection17 (73.9%)3 (6.4%)<0.01
Viral infection15 (65.2%)2 (4.2%)<0.01
 CMV10 (43.5%)1 (2.1%)<0.01
 HCV 5/8 (62.5%)1/15 (6.7%)<0.01

InfectionGroup KT-L ( ) Group KT-H ( ) value
IMK < 225IMK > 225

Bacterial infection1 (5.3%)1 (5%)n.s.
Viral infection7 (36.8%)2 (10%)0.046
 BKV1 (5.3%)2 (10%)n.s.
 CMV3 (15.8%)0 n.s.
 VZV2 (10.5%)0 n.s.
 HSV1 (5.3%)0 n.s.

CMV: cytomegalovirus, HCV: recurrence of hepatitis C infection, BKV: BK virus, VZV: varicella-zoster virus, HSV: herpes simplex virus, and n.s.: not significant.