Research Article
Interpretation of ANA Indirect Immunofluorescence Test Outside the Darkroom Using NOVA View Compared to Manual Microscopy
Table 3
Clinical sensitivity and specificity.
| | Assay | Sensitivity % (95% CI) | Specificity % (95% CI) | Excluding RA samples specificity % (95% CI) |
| | Manual IIF, 1 : 40 dilution | 60.5 (50.9–69.6) | 89.5 (83.3–94.0) | 93.9 (87.3–97.7) | | NOVA View, 1 : 40 dilution | 61.4 (51.8–70.4) | 90.9 (85.0–95.1) | 94.9 (88.6–98.3) | | Manual IIF, 1 : 80 dilution | 49.1 (39.6–58.7) | 94.4 (89.3–97.6) | 98.0 (92.9–99.8) | | NOVA View, 1 : 80 dilution | 50.9 (41.3–60.4) | 94.4 (89.3–97.6) | 97.0 (91.4–99.4) |
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