Differential Transcript Profiles of MHC Class Ib(Qa-1, Qa-2, and Qa-10) and Aire Genes during the Ontogeny of Thymus and Other Tissues
Figure 2
Comparisons of gene expression profiles of MHC class Ib and Aire during development of thymus, lymphoid, and nonlymphoid tissues in C57BL/6 mice. Relative quantification (RQ) obtained from (a) thymus, (b) liver, (c) intestine, (d) spleen, (e) placenta, and (f) brain is representative of the mean values of 2−ΔΔCt. obtained from comparisons of the four genes in each tissue independently. Tissue samples were obtained in triplicate from different animals for each age analyzed. Each experiment was independently performed at least three times. Data were analyzed statistically by two-way ANOVA followed by the Bonferroni multiple comparison test. Values close to the level of significance are marked with ().
