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Journal of Immunology Research
Volume 2014, Article ID 169082, 14 pages
http://dx.doi.org/10.1155/2014/169082
Research Article

Association of TNF-α with Impaired Migration Capacity of Mesenchymal Stem Cells in Patients with Systemic Lupus Erythematosus

Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China

Received 21 May 2014; Accepted 7 September 2014; Published 24 November 2014

Academic Editor: Enrico Maggi

Copyright © 2014 Linyu Geng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1: Associations of the migration rate with clinical manifestations: a. SLEDAI score, b. white blood cells, c. hemoglobin, d. platelet, e. urine protein, f. serum creatinine, g. complement 3, h. complement 4, i. ESR, j. arthralgia, k. febrile, l. vasculitis, m. pneumonia, n. serositis.

Supplementary Figure 2: Associations of the migration rate with various treatment drugs. a, b. BMSCs from patients taking high doses of steroids (a) or HCQ (b) tended to have decreased migration rate. c,d. MMF (c) or CYC (d) treatment do not seem to have effect on SLE BMSCs migration rate.

  1. Supplementary Materials