Novel Clinical and Diagnostic Aspects of Antineutrophil Cytoplasmic Antibodies

Figure 5

Receiver operation characteristics (ROC) analysis of 292 GPA serum samples tested together with 1356 disease controls using a novel PR3 CLIA revealed an area under the curve (AUC) value of 0.78 (95% CI 0.74–0.83), resulting in a clinical sensitivity and specificity of 62.7% (95% CI 56.8–68.2%) and 98.0% (95% CI 97.1–98.7%), respectively.