Dose of Incorporated Immunodominant Antigen in Recombinant BCG Impacts Modestly on Th1 Immune Response and Protective Efficiency against <i>Mycobacterium tuberculosis</i> in Mice

<table>ELISPOT assays of<i> M. tb</i>-specific IFN-<i>γ</i> producing splenocytes in (r)BCGs-vaccinated mice. Eight weeks after vaccination, splenocytes were isolated and then incubated with purified Ag85A, ESAT-6, or PPD for<i> ex vivo</i> IFN-<i>γ</i> ELISPOT assay. Column diagram for mean number of spot-forming units (SFU) ± SD (<svg height="11.225" id="M5" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> (one-way ANOVA).</table>

Journal of Immunology Research

fig2

Figure 2

Figure 2: Dose of Incorporated Immunodominant Antigen in Recombinant BCG Impacts Modestly on Th1 Immune Response and Protective Efficiency against <i>Mycobacterium tuberculosis</i> in Mice 

Figure 2 | Dose of Incorporated Immunodominant Antigen in Recombinant BCG Impacts Modestly on Th1 Immune Response and Protective Efficiency against Mycobacterium tuberculosis in Mice 