Review Article

The Roles of Regulatory B Cells in Cancer

Table 1

The immunophenotype and naming of the regulatory B cells in mouse and human.

SpeciesMarker/phenotypeNamingReferences

Human CD24hi CD27+B10 cells[17]
CD19+ CD25hi CD86hi CD1dhiBregs[19]
CD19+ CD24hi CD38hiBregs[18]
CD19+ CD38+ CD1d+ IgM+ CD147+ GrB+GrB+ Bregs[24]

MouseCD19+ CD5+ CD1dhiB10 cells[5]
B220+ CD21int CD62int IgMint CD23hi CD1dhiCD1dhi MLN B cells [12]
CD1dhi CD21hi CD23āˆ’ CD24hi IgMhi IgDloMarginal zone B cells[13]
CD19+ CD21hi CD23hi CD24hi IgDhi IgMhi CD1dhiTransitional 2 marginal-zone precursor (T2-MZP) [13]
Tim-1+Tim-1+ Bregs [14]
CD1dlo CD11blo CD2 1/CD35lo CD25+ CD69+ CD72hi CD185āˆ’ CD196+ IgM+ IgD+Adipose IL-10+ B cells[16]
CD19+ B220+ CD25+Tumor-evoked regulatory B cells (tBregs)[53]