Appropriate Development of the Liver Treg Compartment Is Modulated by the Microbiota and Requires TGF-β and MyD88

Figure 6

The increased frequency of FoxP3⁺CD4⁺ cells in postnatal liver is independent of TLR2. Liver and spleen FoxP3⁺CD4⁺ cell frequency data are shown for 8- to 9-day-old littermate C57Bl/6-background Tlr2 ^+/+ mice and Tlr2 ^−/− mice. to 5 mice per genotype. Statistical analyses used the nonparametric Mann-Whitney test.