Anti-MDA5 Antibodies in a Large Mediterranean Population of Adults with Dermatomyositis
Figure 2
Representation of the anti-MDA5 ELISA test results in patients with dermatomyositis (DM) () and controls groups: polymyositis (PM) (), systemic sclerosis (SSc) (), systemic lupus erythematosus (SLE) (), and healthy controls (). Panel (b) shows anti-MDA5 ELISA of patients with DM () and individual subgroups of DM patients: rapidly progressive-interstitial lung disease (RP-ILD) () and clinically amyopathic dermatomyositis (CADM) (). The cut-off value for a positive result was established at 0.188 absorbance units which corresponded to 2 standard deviations above the mean value obtained for the 25 healthy controls (dashed line).
