Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO
Figure 6
Effect of inflammasome activation on IL-6 release. IL-6 release from WT and MARCO−/− AM in response to silica (100 μg/mL), LPS (20 ng/mL), or silica and LPS. Mean ± SEM IL-6 from cultured AM where white bars indicate WT AM and grey bars indicate MARCO−/− AM. Triple asterisk indicates compared to WT at corresponding treatment, indicates compared to control in the corresponding mouse strain, per experimental group.
