Fusion-Expressed CTB Improves Both Systemic and Mucosal T-Cell Responses Elicited by an Intranasal DNA Priming/Intramuscular Recombinant Vaccinia Boosting Regimen
Figure 1
Humoral and cellular immune responses at systemic level. (a) Ovalbumin specific T-cell responses in spleen. The cellular responses elicited in rTTV-OVA-CTB boosting groups were significantly stronger than those elicited in rTTV-OVA boosting groups. (b) Ovalbumin specific antibody responses in serum. OVA specific IgG titers elicited by adjuvant groups tended to be lower than the nonadjuvant group, but no statistical significance was reached. .
