Autoantibodies Targeting AT1 Receptor from Patients with Acute Coronary Syndrome Upregulate Proinflammatory Cytokines Expression in Endothelial Cells Involving NF-κB Pathway

Figure 1

The titers of AT1-AAs in the sera sample collected from each group of patients with CHD measured by repeated ELISA. Titers of AT1-AAs in different group of patients and the healthy control group were all shown in the figure. The positive patient was defined as the titer higher than 1 : 40. AT1-AAs in ACS group were significantly different from the SCD, NCD, and control groups () and the positive rate was 50%, 31%, 19%, and 6%. The AT1-AAs used for the following experiments were collected from the 5 positive sera samples of ACS group separately, with the antibody titer higher than 1 : 120.