Table 2: Clinical sensitivity and specificity.

AssaySensitivity % (95% CI)Specificity % (95% CI)LR+/LR−

QF h-tTG IgA 90.5 (81.5–96.1)99.3 (96.0–100.0)124.95/0.10
h-tTG IgA FEIA (equivocal = positive)90.5 (81.5–96.1)99.3 (96.0–100.0)124.95/0.10
h-tTG IgA FEIA (equivocal = negative)75.7 (64.3–84.9)99.3 (96.0–100.0)104.43/0.25
QF h-tTG IgG 35.1 (24.4–47.1)99.3 (96.0–100.0)48.49/0.65
h-tTG IgG FEIA (equivocal = positive)37.8 (26.8–49.9)100.0 (97.4–100.0)+∞/0.62
h-tTG IgG FEIA (equivocal = negative)27.0 (17.4–38.6)100.0 (97.4–100.0)+∞/0.73
QF DGP IgA 70.3 (58.5–80.3)98.6 (94.9–99.8)48.49/0.30
DGP IgA FEIA (equivocal = positive)62.2 (50.1–73.2)97.1 (92.7–99.2)21.45/0.39
DGP IgA FEIA (equivocal = negative)52.7 (40.7–64.4)97.1 (92.7–99.2)18.18/0.49
QF DGP IgG 75.7 (64.3–84.9)96.4 (91.7–98.8)20.89/0.25
DGP IgG FEIA (equivocal = positive)73.0 (61.4–82.6)98.6 (94.9–99.8)50.35/0.27
DGP IgG FEIA (equivocal = negative)56.8 (44.7–68.2)98.6 (94.9–99.8)39.16/0.44