Comparisons of CVID and IgGSD: Referring Physicians, Autoimmune Conditions, Pneumovax Reactivity, Immunoglobulin Levels, Blood Lymphocyte Subsets, and HLA-A and -B Typing in 432 Adult Index Patients
Table 6
Positivity for HLA-B types in 432 adult CVID/IgGSD index patients1.
Type
CVID ()
IgGSD ()
Value of
B*07
29.4 (10)
22.9 (91)
0.3866
B*08
38.2 (13)
25.4 (101)
0.1025
B*13
0
4.3 (17)
0.2414
B*14
2.9 (1)
9.0 (36)
0.1874
B*15
11.8 (4)
14.1 (56)
0.4757
B*18
8.8 (3)
7.3 (29)
0.4708
B*27
2.9 (1)
6.8 (27)
0.3322
B*35
8.8 (3)
14.1 (56)
0.2888
B*37
2.9 (1)
2.3 (9)
0.5634
B*38
8.8 (3)
2.8 (11)
0.0891
B*39
0
3.5 (14)
0.1681
B*40
17.7 (6)
8.8 (35)
0.0894
B*41
0
1.0 (4)
0.7196
B*44
44.1 (15)
30.2 (120)
0.0917
B*45
0
2.3 (9)
0.4747
B*47
0
1.0 (4)
0.7196
B*48
0
0.3 (1)
0.9213
B*49
0
3.8 (15)
0.2863
B*50
0
2.8 (11)
0.3705
B*51
14.7 (5)
8.3 (33)
0.1673
B*52
0
2.5 (10)
0.4366
B*53
2.9 (1)
1.3 (5)
0.3903
B*55
0
3.5 (14)
0.3116
B*56
0
1.3 (5)
0.6624
B*57
2.9 (1)
7.0 (28)
0.3127
B*58
0
0.5 (2)
0.8486
B*60
0
1.3 (5)
0.6624
B*62
2.9 (1)
0.5 (2)
0.2185
HLA, human leukocyte antigen; CVID, common variable immunodeficiency; IgGSD, IgG subclass deficiency. Results are displayed as % (). Comparisons were made with Pearson’s test or Fischer’s exact test, as appropriate.