Capillary Dilation and Rarefaction Are Correlated with Intracapillary Inflammation in Antibody-Mediated Rejection

Table 2

Histological characteristics in different groups.

	ABMR (𝑛=18)	TCMR (𝑛=13)	SG (𝑛=14)	Post hoc
				𝑃12	𝑃13	𝑃23
Histological lesions
PTC inflammation, 𝑛 (%)	18 (100)	0	0	—	—	—
Glomerulitis, 𝑛 (%)	18 (100)	0	0	—	—	—
Tubulitis, 𝑛 (%)	18 (100)	13 (100)	6 (42.9)	—	<0.001	<0.001
Intimal arteritis, 𝑛 (%)	16 (88.9)	5 (38.5)	0	<0.001	<0.001	0.005
Intraglomerular infiltrating cells count (cells/mm^2)	5.90 (1.76–9.30)	0.30 (0.00–2.03)	0.00 (0.00–0.60)	0.001	<0.001	0.518
Interstitial
CD4 (cells/mm^2)	322 (165–426)	276 (181–372)	98 (69–147)	0.477	<0.001	<0.001
CD8 (cells/mm^2)	266 (171–352)	204 (160–424)	96 (45–129)	0.863	<0.001	<0.001
CD4/CD8	1.16 (0.78–1.54)	1.15 (0.97–1.23)	1.18 (0.95–1.33)	0.766	0.849	0.655
CD68 (cells/mm^2)	624 (398–924)	476 (202–614)	94 (50–194)	0.110	<0.001	<0.001
HLA-DR	0.36 (0.12–0.67)	0.20 (0.00–0.67)	0.00 (0.00–0.06)	0.365	0.004	0.049

Abbreviations: ABMR: antibody-mediated rejection; TCMR: T cell-mediated rejection; SG: stable graft; HLA: human lymphocyte antigen; PTC: peritubular capillary.
𝑃₁₂ means 𝑃 value for ABMR group and TCMR group; 𝑃₁₃ means 𝑃 value for ABMR group and SG group; 𝑃₂₃ means 𝑃 value for TCMR group and SG group.