Biological activities of IL-17F. IL-17F has multiple biological activities. IL-17F is produced by several cell types including Th17 cells and bronchial epithelial cells. IL-17F can induce various asthma-related cytokines, chemokines, and adhesion molecules in bronchial epithelial cells, eosinophils, fibroblasts, airway smooth muscle cells, and vein endothelial cells, and thereby contributes to the pathogenesis of asthma.
