Journal of Immunology Research / 2014 / Article / Fig 2

Research Article

Effects of Pristane Alone or Combined with Chloroquine on Macrophage Activation, Oxidative Stress, and Th1/Th2 Skewness

Figure 2

Effects of pristane alone or combined with chloroquine on cytological characteristics in blood and bone marrow. Wright-Giemsa staining was performed in peripheral blood (a) and bone marrow (b) smears. Hemophagocytosis (arrows), poikilocytosis, polychromasia, hypochromia, and anisocytosis of erythrocytes were observed in blood smear of pristane-treated mice. Bone marrow cytology depicted hypocellularity in erythroid progenitors, poikilocytosis, and nonerythroid lineage clonal expansion following treatment with pristane for 12 weeks or 24 weeks. And the severity of poikilocytosis was attenuated in the presence of chloroquine.
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