|
| References |
Number of cases | Age, years | Female sex | Color | Disease duration, years | RF manifestations | APS manifestations | SLE associated | ASO | Antiphospholipid antibody | RF prophylaxis |
|
| Soeiro et al., 2012 [6] | 1 | 30 | 100% | Brown |
1.5 RF-APS | Carditis: + (with mitral valve replacement, right bundle branch block)
Chorea: +
Arthritis: − | Arterial: embolic stroke, AMI
Venous: −
Obstetric: −
Thrombocytopenia: +
Livedo: −
Chorea: + | Yes | 786 UI/mL | aCL IgM: + (14 MPL) | Penicillin G benzathine 100% |
|
|
Camargo et al., 2012 [7] | 73 APS, 5 RF-APS | 37.4 | 100% | 100% white | 5.6 RF
5.6 APS | Carditis (ECO abnormal): 100%
Chorea: 2/5
Arthritis: − | Arterial: stroke 4/5
Venous: DVT 2/5
Obstetric: −
Thrombocytopenia: 1/5
Livedo: −
Chorea: 2/5 | No | Increased in acute phase: 100% | aCL IgG: 2/5
aCL IgM: 3/5
LAC: 2/5
Anti-β2GPI(IgG): 3/5 | Penicillin G benzathine 100% |
|
| Alcock et al., 2011 [8] | 1 | 44 | 100% | — | 27 RF
24 APS | Carditis: + (ECG: block first degree
ECO: mitral thickening)
Chorea: +
Arthritis: + | Arterial: stroke
Venous: −
Obstetric: abortion, fetal and maternal hypertension
Thrombocytopenia: +
Livedo: −
Chorea: + | No | 883 UI/mL, Anti-DNAase B: 960 UI/mL | aCL: +
LAC: +
anti-β2GPI (IgG): 117 SGU/mL | Penicillin 100% |
|
| Izhevsky et al., 2004 [9] | 1 | 29 | 0% | — |
-RF9 APS | Carditis: +
(block AV first and third grades)
Chorea: −
Arthritis: +
Subcutaneous nodule: + | Arterial: AMI (with CRA and successful resuscitation)
Venous: DVT
Thrombocytopenia: −
Livedo: −
Chorea: − | No | Increased | aCL IgG: +
LAC: + | Penicillin G benzathine 100% |
|
| Amital et al., 1999 [10] | 1 | 45 | 100% | — | 35 RF
12 APS | Carditis: + (admitted for mitral valve replacement)
Chorea: +
Arthritis: − | Arterial: stroke, splenic infarction
Venous: −
Obstetric: − Thrombocytopenia: −
Livedo: −
Chorea: + | Yes | — | LAC: + | Prophylaxis with antibiotic |
|
| Fung et al., 1998 [11] | 2 | Case 1: 22
Case 2: 31 | 100% | 1 white,
1 not described | Case 1: −
Case 2: 15 RF
2 APS | Case 1:
Carditis: + (ECO: rheumatic valve disease, systolic murmur)
Chorea: +
Arthritis: −
Case 2:
Carditis: + (mitral murmur)
Chorea: +
Arthralgia: + | Cases 1 and 2:
Arterial: −
Venous: −
Obstetric: −
Thrombocytopenia: −
Livedo: −
Chorea: + | Case 1: anti-dsDNA positive (35%)
Case 2: ANA positive | Case 1: normal, anti-DNAase B: 1280 UI/mL
Case 2: 451 UI/mL |
Case 1: aCL IgM: + (14 MPL)
Case 2: aCL: + | Case 1: oral penicillin
Case 2: sulfadiazine |
|
